Searchable abstracts of presentations at key conferences in endocrinology

ea0011p234 | Cytokines and growth factors | ECE2006

Possible predictive value of IGF-II mRNA expression in breast cancer (BC)

Giani CG , Giustarini EG , Fierabracci PF , Campani DC , Lippman MEL

Insuline like growth factor II (IGF II) is an important regulator of neoplastic growth and it is stromal in origin. Estrogen and Progesterone receptor (ER, PR) are considered a good prognostic predictors in BC. The aim of the study was to evaluate the impact of IGF II mRNA expression in the clinical outcome in breast malignancy. The study group included 75 women (mean age ±S.D.=53.3±15.6 yr) submitted to radical mastectomy for ductal infiltrating breas...